• 研究组主要研究兴趣及方向：

神经免疫及抑郁症神经调控

• 个人简况：

1. 导师类型：科学学位硕士生导师、专业学位硕士生导师

2. 专业技术职称：主任医师

3. 行政职务：中国科学技术大学附属第一医院院长

4. 招生专业：内科学/神经病学

5. 简介：

教授、主任医师、博士生导师，入选国家重点人才、人社部百千万人才工程“有突出贡献中青年专家”、皖江学者特聘教授、安徽省学术技术学术带头人、享受国务院津贴。主持国家自然基金5项、作为主要参与人参与国家973子课题2项和国家重点项目1项、获得安徽省杰出青年自然科学基金1项，工作致力于临床的转化和应用。兼任中华医学会罕见病学会委员，安徽省医学会罕见病学分会主任委员等，代表性论文有Nature Neuroscience, Nature Communications, Biological Psychiatry, Molecular Psychiatry, Nature Genetics, PNAS等杂志。多次获得安徽省科技进步奖。

 ①学术任职情况：

中华医学会神经病学分会青年委员会委员、国家卫计委脑血管病防治中青年专家、中国卒中学会血管性认知障碍委员会常委、中国医师协会神经内科分会青年委员会委员、中国卒中学会青年理事会委员、中国老年医学会认知障碍分会青年委员会副主任委员、安徽省医学会罕见病学分会主任委员、安徽省继续教育委员会副秘书长、安徽省卒中学会副会长等。

 ②个人教育及工作经历：

个人教育

1998-09-01至2003-06-30 安徽医科大学 临床医学 学士

2005-09-01至2008-06-30 安徽医科大学 神经病学 硕士

2008-09-01至2011-06-30 安徽医科大学 神经病学 博士

工作经历

2018.12-至今安徽医科大学第一附属医院神经内科主任医师

2019.09-至今安徽医科大学第一附属医院神经内科教授

2021.10-2025.01安徽医科大学第二附属医院神经内科执行院长

2025.02-2026.02安徽医科大学神经内科副校长

2026.02-至今中国科学技术大学附属第一医院（安徽省立医院） 院长

• 联系方式：

5. mail: tianyh@ustc.edu.cn

• 近五年发表重要学术论文：

2026年：

1. Ji Gong-Jun, Xu Wenqiang, Zhang Juan, Li Qianqian, Yang Yinian, He Kongliang, Yu Fenqiong, Zhu Chunyan, Jiang Xiao, Jing Liang, Hu Panpan, Yanghua Tian*(co-corresponding author), Wang Kai. Distinct antidepressant therapies act on a common brain network. Nat Commun. 2026 Jan 3;17(1):1176. doi: 10.1038/s41467-025-67945-5. PMID: 41484145; PMCID: PMC12858948.

2025年：

1. Dongpeng Wu, Shaoyang Wang, Hongping Wang, Jiahua Zhang, Yanghua Tian*(last-corresponding author). Neural mechanisms and neuromodulation therapies for non-suicidal self-injury. Mol Psychiatry. 2025 Jul 16. doi: 10.1038/s41380-025-03125-7. Epub ahead of print. PMID: 40670680.

2. Qing Tong, Feng Geng, Meiling Wang, Sujie Kang, Zixuan Guo, Xiaoyan Ye, Li Zhu, Sisi Xie, Qianqian Li, Guixian Xiao, Fengqiong Yu, Chunyan 3. Zhu, Yanghua Tian*(co-corresponding author), Kai Wang*, Lei Zhang*. Effects of transcranial alternating current stimulation (tACS) on attentional bias in non-suicidal self-injury adolescents: A single-blind sham-controlled study. Brain Stimul. 2025 Jul-Aug;18(4):1184-1186. doi: 10.1016/j.brs.2025.06.010. Epub 2025 Jun 12. PMID: 40516647

4. Siyu Fan, Yulin Zhang, Rui Qian, Jie Hu, Hao Zheng, Wentao Dai, Yang Ji, Yue Wu, Xiaohui Xie, Si Xu*, Gong-Jun Ji*, Yanghua Tian*(last-corresponding author), Kai Wang. Genetic and molecular basis of abnormal BOLD signaling variability in patients with major depressive disorder after electroconvulsive therapy. Transl Psychiatry. 2025 Apr 2;15(1):117. doi: 10.1038/s41398-025-03330-6. PMID: 40175334; PMCID: PMC11965524.

2024年：

1. Yuan-Yuan Guo, Ming-Rui Xia, Rong Ye, Tong-Jian Bai, Yue Wu, Yang Ji,Yue Yu, Gong-Jun Ji, Kai Wang, Yong He*, Yanghua Tian*(last-corresponding author). Electroconvulsive Therapy Regulates Brain Connectome Dynamics in Patients With Major Depressive Disorder. Biol Psychiatry. 2024 Dec 15;96(12):929-939. doi: 10.1016/j.biopsych.2024.03.012. Epub 2024 Mar 21. PMID: 38521158.

2. Jing Du, Shugang Cao, Lan Xia, Qi Li, Yanghua Tian*(last-corresponding author). Corrigendum: Plasma exchange for two patients with autoimmune GFAP astrocytopathy with rapid progression to respiratory failure: a case report. Front Immunol. 2024 Jan 16;15:1366725. doi: 10.3389/fimmu.2024.1366725. Erratum for: Front Immunol. 2023 Oct 05;14:1265609. doi: 10.3389/fimmu.2023.1265609. PMID: 38292871; PMCID: PMC10825565.

3. Shugang Cao, Yunfei Zhu, Xiaosan Wu, Jing Du, Si Xu, Ping Cui, Qi Li, Mingwu Xia, Qun Xue*, Yanghua Tian*(last-corresponding author). Asymptomatic spinal lesions in patients with AQP4-IgG-positive NMOSD: A real-world cohort study. Ann Clin Transl Neurol. Published online February 4, 2024. doi:10.1002/acn3.52007

4. Xia Zhu, Ji-Ye Huang, Wan-Ying Dong, Hao-Di Tang, Si Xu, Qielan Wu, Huimin Zhang, Ping-Kai Cheng, Yuxin Jin, Meng-Yu Zhu, Wan Zhao, Yu Mao, Haitao Wang, Yan Zhang, Hao Wang, Wenjuan Tao*, Yanghua Tian*(co-corresponding author), Li Bai*, Zhi Zhang*. Somatosensory cortex and central amygdala regulate neuropathic pain-mediated peripheral immune response via vagal projections to the spleen. Nat Neurosci. Published online January 30, 2024. doi:10.1038/s41593-023-01561-8

2023年：

1. Jing Du, Shugang Cao, Lan Xia, Qi Li, Yanghua Tian* (last-corresponding author). Plasma exchange for two patients with autoimmune GFAP astrocytopathy with rapid progression to respiratory failure: a case report. Front Immunol. 2023;14:1265609. Published 2023 Oct 5. doi:10.3389/fimmu.2023.1265609

2. Yangting Xu, Yuhan Zhang, Di Zhao, Yanghua Tian* (co-corresponding author), Ti-Fei Yuan. Growing placebo response in TMS treatment for depression: a meta-analysis of 27-year randomized sham-controlled trials. Nat. Mental Health. 2023 Sep 25. https://doi.org/10.1038/s44220-023-00118-9

3. Shugang Cao, Jing Du, Sidi Pan, Juanjuan Zhang, Si Xu, Ling Wei, Yanghua Tian* (last-corresponding author). Case Report: Ofatumumab treatment in a patient with rituximab-intolerant refractory autoimmune GFAP astrocytopathy. Front Immunol. 2023 May 8;14:1164181. doi: 10.3389/fimmu.2023.1164181.

Guanglu Li, Jiajia Zhu, Xingqi Wu, Tingting Liu, Panpan Hu, Yanghua Tian* (co-corresponding author), Kai Wang. Baseline free water within the visual processing system predicts future psychosis in Parkinson disease. Eur J Neurol. 2023 Apr;30(4):892-901. doi: 10.1111/ene.15668.

4. Gong-Jun Ji, Jiao Li, Wei Liao, Yingru Wang, Lei Zhang, Tongjian Bai,Ting Zhang,Wen Xie,Kongliang He,Chuyan Zhu,Juergen Dukart,Chris Baeken,Yanghua Tian*(co-corresponding author),Kai Wang. Neuroplasticity-Related Genes and Dopamine Receptors Associated with Regional Cortical Thickness Increase Following Electroconvulsive Therapy for Major Depressive Disorder. Mol Neurobiol. 2023 Mar;60(3):1465-1475. doi: 10.1007/s12035-022-03132-7. 36469225.

2022 年：

1. Yumeng Xin, Tongjian Bai, Ting Zhang, Yang Chen, Kai Wang, Shan Yu, Ning Liu, Yanghua Tian* (last-corresponding author). Electroconvulsive therapy modulates critical brain dynamics in major depressive disorder patients. Brain Stimul. 2022;15(1):214-225. doi:10.1016/j.brs.2021.12.008.

2. Jinping Xu, Wenfei Li, Tongjian Bai, Jiaying Li, Jinhuan Zhang, Qingmao Hu, Jiaojian Wang, Yanghua Tian* (last-corresponding author), Kai Wang. Volume of hippocampus-amygdala transition area predicts outcomes of electroconvulsive therapy in major depressive disorder: high accuracy validated in two independent cohorts. Psychol Med. 2022;1-10. doi:10.1017/S0033291722001337.

3. Xingqi Wu, Gong-Jun Ji, Zhi Geng, Lu Wang, Yibing Yan, Yue Wu, Guixian Xiao, Liying Gao, Qiang Wei, Shanshan Zhou, Ling Wei, Yanghua Tian* (co-corresponding author), KaiWang. Accelerated intermittent theta-burst stimulation broadly ameliorates symptoms and cognition in Alzheimer's disease: A randomized controlled trial. Brain Stimul. 2022;15(1):35-45. doi:10.1016/j.brs.2021.11.007.

• 本人承担科研项目：

• 本人成果获奖情况