• 研究组主要研究兴趣及方向：

1.间充质干细胞来源细胞外囊泡在组织再生修复和肿瘤治疗中的作用；

2.工程化细胞外囊泡的构建及其生物医学应用；

3.细胞外囊泡诊断标志物的挖掘与应用。

• 个人简况：

1. 导师类型：科学学位硕士生导师

2. 专业技术职称：副研究员

3. 行政职务：科研处副处长（挂职）

4. 招生专业：临床检验诊断学

5. 简介：

医学博士，博士后，副研究员，中国科学技术大学附属第一医院科研处副处长（挂职）、集团检验科质量组长，安徽省E类高层次人才/合肥市D类高层次人才（市级领军人才）。主持国家自然科学基金等国家级、省级课题4项，参与国自然面上项目等课题2项；以第一及通讯作者（含共同）在J Nanobiotechnology、Biomaterials、CHEM ENG J、Biomater Res、Adv Healthc Mater等期刊发表SCI论文19篇（ESI高被引论文1篇）,论文累计他引超2500次，H指数24；参编出版细胞外囊泡中英文专著各1部；申请国内外发明专利20余项，授权10余项。

①学术任职情况：

合肥市预防医学会地方病与寄生虫病防治专委会委员

Exploration、iMeta和Nano TransMed期刊青年编委

②个人教育及工作经历（从大学开始写起）：

2010/09–2015/07, 蚌埠医科大学，医学检验，学士

2015/09–2018/07,江苏大学,临床检验诊断学,硕士,导师:许文荣

2018/09–2022/07,江苏大学,临床检验诊断学,博士,导师:许文荣

2022/09–2025/08，中国科学技术大学，博士后，合作导师：程临钊、王保龙

2022/08–2025/11，中国科大附一院检验科，助理研究员、主管技师、质量组长

2025/12–至 今，中国科大附一院检验科，副研究员、科研处副处长、质量组长

• 联系方式：

E-mail:peipeiwu@ustc.edu.cn

电话：18852867995

• 近五年发表重要学术论文：

1. Zhong Liu#,Xinyu Zhu#,Jun Cheng#,Kewei Li#,Yang Lou,Xiaopeng Sun,Yuhong Fan,Min Wang,Hui Qian,Yanbin Liu,Hua Ding*,Song Guo*,Peipei Wu*,Qiang Fu*. Engineered small extracellular vesicles-integrated multifunctional hydrogel reprograms the wound immune microenvironment for accelerated skin repair. Chemical Engineering Journal. 2026 Nov 1;547: 180867.

2.  Xingyu Zhu#, Zhong Liu#, Kewei Li#, Yuhong Fan#, Kangjia Yang, Xiaopeng Sun,Hang Shi, Lixuan Sun, Yang Lou, Min Wang,Peipei Wu*, Hui Qian*, Qiang Fu*, Hua Ding*. GDNF-enriched small extracellular vesicle-loaded ROS-scavenging hydrogel promotes neural regeneration after spinal cord injury. Advanced Healthcare Materials. 2026 Oct 5: e71806. https://doi.org/10.1002/adhm.71806. Epub ahead of print.

3. Xinxin Zhao#,Dongmei LV#,Min Wang#,Qinyu Guo; Yidi Gao,Wenxiang Fang*,Wenlong Zhang*,Peipei Wu*. Nanomedicine novel strategies: Deciphering the EV-metabolic axis as a natural nanocarrier network in lung cancer progression and cachexia. Journal of Nanobiotechnology. 2026 Apr 9;24(1):486.

4. Peipei Wu#,Zhangfei Wang#,Yongping Sun#,Zhixiang Cheng*,Min Wang*,Baolong Wang*. Extracellular vesicles: A new frontier in diagnosing and treating graft-versus-host disease after allogeneic hematopoietic cell transplantation. Journal of Nanobiotechnology. 2025 Mar 26; 23(1):251.

5. Can Jin#,Lingling Xue#,Leilei Zhang,Lixia Yu*,Peipei Wu*,Hui Qian*. Engineered nanoparticles for theranostic applications in kidney repair. Advanced Healthcare Materials. 2025 Jan;14(1):e2402480.

6. Peipei Wu^(#)(*), Min Wang#, Can Jin#, Linli Li, Yuting Tang, Zhangfei Wang, Xianwen Wang,Wenrong Xu*,Hui Qian*. Highly efficient delivery of novel miR-13896 by human umbilical cord mesenchymal stem cell-derived small extracellular vesicles inhibits gastric cancer progression by targeting ATG2A-mediated autophagy. Biomaterials Research. 2024 Dec 18;28:0119.

7. Kewei Li#,Zhong Liu#,Peipei Wu#,Shenyuan Chen,Min Wang,Wenhui Liu,LeileiZhang,Song Guo,Yanbin Liu,Pengcheng Liu,Beiting Zhang,Lin Tao,Hua Ding*,Hui Qian*,Qiang Fu*. Micro electrical fields induced MSC-sEVs attenuate neuronal cell apoptosis by activating autophagy via lncRNA MALAT1/miR-22-3p/SIRT1/AMPK axis in spinal cord injury. Journal of Nanobiotechnology. 2023 Nov 27;21(1):451.

8. Peipei Wu#,Yuting Tang#,Can Jin#,Min Wang#,Linli Li,Zhong Liu,Hui Shi,ZixuanSun,Xiaomei Hou,Wenya Chen,Wenrong Xu*,Hui Qian*. Neutrophil membrane engineered HucMSC sEVs alleviate cisplatin-induced AKI by enhancing cellular uptake and targeting. Journal of Nanobiotechnology. 2022 Aug 1;20(1):353.

• 本人承担在研科研项目：(仅限于主要负责人)